This is a retrospective cohort of infants and children admitted to Primary Children's Medical Center (PCMC) from January 2001 to December 2010 who received high-dose barbiturate therapy for RICH ...

For permission requests, please contact NEJM Reprints at [email protected] The patients were 4 adult females, twenty to forty years old, admitted to the Los Angeles County Hospital with acute ...

Dr. James Bernat, a professor of neurology at Dartmouth Medical School, says that a drug-induced coma can be a helpful tool to lower intracranial pressure. He talks about how and when doctors ...

RECENT clinical studies have demonstrated that osmotic diuresis, with or without urinary alkalinization, will accelerate the renal excretion of drug in patients with barbiturate intoxication. 1–5 When ...

During the 10 yr studied, 778 TBI patients received mechanical ventilation for 2 days or more and 36 (5%) met study criteria. Ten (28%) patients had RICH controlled (ICP < 20 mm Hg) within 6 hours ...