Fatty acid oxidation (FAO) disorders comprise a heterogeneous group of inborn errors of metabolism that impair the mitochondrial capacity to convert fatty acids into energy. These inherited conditions ...

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...

While C13 fatty acid remains elusive in human plasma, new findings reveal its microbial origins, unique metabolic pathways, and potential as a biomarker for understanding how diet and the gut ...

Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated with the rapid rise in insulin resistance, ...