The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

A new generation of engineered immune cell destroys cancer cells in mice 1 as effectively as conventional CAR-T-cell ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

"Our goal is to be very precise, where we can deliver just the gene that's missing and really target the circuit. Because of that, it can be much safer, more effective, and significantly reduce side ...

Researchers discovered that targeting epigenetic proteins Menin and DOT1L can permanently silence cancer-driving genes. The ...

US biotech firm Fractyl Health is developing Rejuva, an experimental gene therapy that may mimic GLP-1 drugs for years after ...

Dr. Rebecca Ahrens-Nicklas and Dr. Kiran Musunru crafted a bespoke treatment that has successfully corrected the genetic ...

Forbes contributors publish independent expert analyses and insights. A patient in a late-stage gene editing trial for a rare heart condition died from fatal liver complications after receiving an ...

The new method is designed to focus specifically on pain-related signals, without interfering with normal activity in other parts of the brain. A new preclinical study has identified a gene therapy ap ...

Precision DNA editing gene therapy achieves deep remissions in aggressive leukemia previously considered incurable.

A gene transfer approach to treating the bleeding disorder hemophilia B remains safe and effective long-term, as scientists from St. Jude Children's Research Hospital and University College London ...