A joint X-ray/neutron diffraction study has enabled the direct observation of a hydronium ion coordinated by three amino-acid residues of an enzyme. This sighting will affect our views on how enzymes ...
Acid catalysis by hydronium ions is ubiquitous in aqueous-phase organic reactions. Here we show that hydronium ion catalysis, exemplified by intramolecular dehydration of cyclohexanol, is markedly ...