Research has shown that dopamine (DA) plays a key role in how the body regulates the production of insulin. Typically, insulin is secreted by beta-cells in the pancreas in response to glucose—a ...

Diabetes is a lifelong, chronic health condition caused by abnormalities in the body’s production and use of the hormone insulin. Research has shown that the feel-good hormone, dopamine (DA), plays a ...

Researchers elucidate how BHLHE40, a transcriptional repressor activated in pancreatic β-cells as a response to hypoxia, inhibits the expression of the MAFA protein, thereby leading to impaired ...

After an initial chemical screening, researchers at the University of Pennsylvania and Weill Cornell Medicine identified the Chk1/Chk2 dual inhibitor AZD-7762 among the strongest to induce insulin ...

Type 2 diabetes (T2D) is characterized by persistent hyperglycemia (high glucose in blood) that leads to hypoxia (low oxygen condition) in pancreatic β-cells. T2D is a chronic metabolic disorder that ...

Researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little. Just over a century has passed since the ...

Please provide your email address to receive an email when new articles are posted on . “Fatty pancreas is associated with insulin resistance and increased insulin secretion cross-sectionally in ...