A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

Chronic sleep disruption doesn't just leave people tired and irritable. It may quietly undermine the gut's ability to repair ...

A gastroenterologist explains the latest findings.

Supplementing the guts of older mice with poop from younger ones has revealed the key role microbes play in intestinal stem ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection ...

Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Drosophila melanogaster has long served as a powerful model for dissecting the principles of tissue homeostasis and regeneration. Within the adult midgut, intestinal stem cells (ISCs) perform the ...

An international study led by Paolo Fiorina from Boston Children’s Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...