This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

The patient noted that she was initiated on naproxen by her primary care physician 2 weeks prior to her presentation. A recently published report describes the case of an 88-year-old female patient ...

A consistent recent finding has been the strong association between hyponatremia and fractures. Initially, two case control studies reported the association of mild asymptomatic hyponatremia with bone ...

Dear Dr. Roach: My husband had a nonstop coughing incident for a night and day after a feast, which landed him in the emergency room. He was found to have extremely low sodium levels (118-120 mEq/L), ...

Empagliflozin is a potential treatment for outpatients with chronic hyponatremia due to the syndrome of inappropriate antidiuresis (SIAD), new data suggest. The sodium-glucose cotransporter 2 (SGLT2) ...

As a general rule, the treatment of hyponatremia should be directed at the primary underlying disorder because such treatment might, in itself, correct the electrolyte imbalance. Thiazide diuretics ...

DEAR DR. ROACH: I am a 75-year-old male who is 6 feet 1 inch tall and weighs 195 pounds. I had a heart attack 20 years ago, and I was warned to cut down my salt intake. From that time on, I stopped ...

Diane was brought to the emergency department via ambulance from home where her husband called 911 because she was acting strangely. According to Diane’s husband, she was intermittently acting ...

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia. We describe two infants whose clinical and laboratory evaluations were consistent with the ...