C&EN

Design of a True Bivalent Ligand with Picomolar Binding Affinity for a G Protein-Coupled Receptor Homodimer

Biomaterials and Nanomedicine, Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Barcelona Science Park, 08028 Barcelona, Spain Combinatorial ...
People

Boy, 7, Who Says He Was Gucci in a Past Life, Goes Viral for His Impressive Work as a Dressmaker

Max Alexander, 7, began making dresses at only 4 years old — and he's already selling his work internationally and getting commissions from celebrities Georgia Slater is a staff editor on the Parents ...
IEEE

Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures

Abstract: Inductive bias in machine learning (ML) is the set of assumptions describing how a model makes predictions. Different ML-based methods for protein-ligand binding affinity (PLA) prediction ...