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  1. GD2 - Wikipedia

    GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the …

  2. Biology of GD2 ganglioside: implications for cancer ...

    GD2 ganglioside is a sialic acid-containing glycosphingolipid, whose structure is characterized by two distinct portions with different physicochemical properties. It is composed of a hydrophobic ceramide …

  3. What Is GD2 and How Is It Targeted in Cancer? - Biology Insights

    Jun 28, 2025 · GD2 is a type of molecule called a disialoganglioside, a complex structure of lipids and sugars. These molecules embed themselves in the outer membrane of cells, where they are involved …

  4. GD2: hopes and challenges for the treatment of pediatric ...

    Aug 21, 2025 · We provide a detailed overview of the investigational and diagnostic methods for evaluating GD2 expression on freshly dissociated tumor samples, tissue sections, or tumor-derived …

  5. GD2 is a Crucial Ganglioside in the Signal Modulation and ...

    Feb 7, 2025 · While various glycosphingolipids were identified as cancer-associated carbohydrate antigens to be used as tumor markers, disialylated gangliosides such as GD3 and GD2 have …